Oswaldo Porchat (1933-2017)

Oswaldo Cruz Foundation - Ministry of Health

Canynge Hall 1933-1969

ust over thirty-five years ago the newly formed Univer-Department of Preventive Medicine was opened at anynge Hall, a former hotel (Plate V), by the then 'hister of Health, Sir Hilton Young. He described the ?Ccasion as the celebration of a marriage of the City Bristol with the fair nymph of knowledge, and Dr. anley Badock, in proposing the vote of thanks, hoped at it would be a lasting and hap...

[Oswaldo Cruz and the serology controversy].

This analysis of the discussion surrounding the efficacy of the plague serum produced by Manguinhos Institute in the early twentieth century begins with an overview of Oswaldo Cruz's service as head of the Public Health Directorship (Diretoria de Saúde Pública). The controversy itself is then addressed, through an exploration of correspondence exchanged by physicians Oswaldo Cruz, Miguel Pereir...

Michael Heidelberger, 1933

Dmd053223 1923..1933

Mefenamic acid (MFA), a carboxylic acid–containing nonsteroidal anti-inflammatory drug, is metabolized into the chemically-reactive MFA-1-O-acyl-glucuronide (MFA-1-O-G), MFA-acyl-adenylate (MFAAMP), and the MFA-S-acyl-coenzyme A (MFA-CoA), all of which are electrophilic and capable of acylating nucleophilic sites on biomolecules. In this study, we investigate the nonenzymatic ability of each MF...